George Lykotrafitis, Ph.D.
Cell biomechanics, sickle cell disease, atomic force microscopy
United Technologies Engineering Building Rm. 374
191 Auditorium Road, Storrs CT 06269
Office Phone:Phone: (860) 486-2439
Fax: (860) 486-5088
BS National Technical University of Athens, Greece, 2001.
MS National Technical University of Athens, Greece, 2001.
Ph.D. National Technical University of Athens, Greece, 2001.
Ph.D. California Institute of Technology, 2005.
The goal of Dr. Lykotrafitis’ laboratory is to study, by combining experimental, clinical, and computational investigation, how changes in the biomechanical properties of cells and subcellular structures influence, and are influenced by, the onset and progression of SCD to support diagnosis, pharmacotherapy and prevention of life threatening complications. The overall objective is to quantitatively understand the biophysical mechanisms related to hydroxyurea and its effect on sickle erythrocytes in vitro. Dr. Lykotrafitis’ laboratory currently combines experimental techniques conducted via AFM with molecular dynamics simulations.
More information about current projects can be found at: