Syam Nukavarapu, Ph.D.
Research Interests: Biomaterials, Stem Cells, Bone and Bone-Cartilage Interface Regeneration, and Bedside Tissue Engineering Methods
263 Farmington Avenue
Farmington, CT 06030
Office Phone: (860)679-4183
PhD Indian Institute of Science (IISc)
Postdoc Lehigh University, and University of Virginia (UVA)
Research in my laboratory involves the development and evaluation of advanced biomaterials and matrix systems for bone and bone-cartilage interface (osteochondral) tissue engineering. Our group is primarily focused to develop methods for rapid stem cell isolation and matrix systems that support cell loading at the bedside to implement Completely Intra-operative Tissue Engineering Strategies (CITES) for on-site therapy/ bedside tissue engineering.
More information about the current research projects can be found at:
Honors and Awards:
Young Investigator Award, AO Foundation, Davos, Switzerland
Mentorship (M-1) award, Connecticut Institute for Clinical and Translational Science (CICATS), University of Connecticut
Junior Investigator Award, Musculoskeletal Transplant Foundation (MTF), Edison, NJ
Nukavarapu SP, Liu H, Deng T, Oyen M, Tamerler C, Advances in Structures, Properties and Applications of Biological and Bioinspired Materials, MRS F13 Symposium Proceedings, Volume 1621, Cambridge Press.
Nukavarapu SP, Freeman J, Laurencin CT. Regenerative Engineering of Musculoskeletal Tissues and Interfaces, Woodhead Publishers, 2015.
PubMed Citations Link:
Google Scholar Citations Link
Mikael PE, Xin X, Urso M, Jiang X, Wang L, Barnes B, Lichtler AC, Rowe DW, Nukavarapu SP. (2014) A potential translational approach for bone tissue engineering through endochondral ossification. IEEE Eng Med Biol Soc. 3925-8.
Amini AR, Nukavarapu SP. (2014) Oxygen Tension Controlled Matrices for Enhanced Osteogenic Cell Survival and Performance. Ann Biomed Eng. 2014;42(6):1261-70.
Igwe J, Mikael P, Nukavarapu SP. (2014). Design, fabrication and in vitro evaluation of a novel polymer-hydrogel hybrid scaffold for bone tissue engineering. J Tissue Eng Regen Med. 8: 131–142.
Nukavarapu SP, Dorcemus D. (2013) Osteochondral Tissue Engineering: Current Strategies and Challenges. Biotechnology Advances, 31, 706-721.
Amini AR, Laurencin CT, Nukavarapu SP. (2012) Differential analysis of peripheral blood- and bone marrow-derived endothelial progenitor cells for enhanced vascularization in bone tissue engineering. J Orthop Res. 30:1507-15.