MARK B. LYLES, M.A., M.S., Ed.S., D.M.D., Ph.D.

Office Phone: (401) 874-5408 

Mark B. Lyles, MA, MS, EdS, DMD, PhD is presently the Liaison to Defense Interactions, Office of the Vice President for Research and Development, the University of Rhode Island.  CAPT Lyles USN (ret) is the past VADM Joel T. Boone Inaugural Chair of Health and Security Studies at the U.S. Naval War College in Newport, RI from 2010 to 2015.  Prior to that he was the Deputy to the Special Assistant to the Surgeon General for Research Program Integration & Mission Development at the U.S. Navy Bureau of Medicine and Surgery, in Washington, DC and the Navy Liaison to the U.S. Army’s Medical Research Programs, Fort Detrick, MD. He also represented the Navy as CBRNE subject matter expert.

Dr. Lyles attended Murray State University earning his B.A. in Chemistry & Cell Physiology in 1978 followed by both an A.S. & B.S. degree in Chemical Technology & Cell Biology respectively in 1981.  He also earned a M.S. degree in Analytical Chemistry and his Ed.S. degree in Higher Education in 1982 conducting his research at the National Center of Toxicological Research EPA / FDA in Pine Bluff, AK.  In 1981, he was a Ph.D. Graduate Fellow in both Physiology and Toxicology at the University of Louisville and in 1982, entered the College of Dentistry at the University of Louisville earning his D.M.D. degree in 1986.  In 1983, he was commissioned as an Ensign in the U.S. Naval Reserve.

Upon graduation in 1986, Dr. Lyles was promoted to the rank of Lieutenant in the U.S. Navy having assignments at the 12th Dental Company, the 22nd Marine Expeditionary Unit /Special Operations Contingency Force (MARG 4/87) ‘World’s Angriest Dog’ and ‘The Battleship’ USS New Jersey BB62. Upon his discharge from active duty in 1991, Dr. Lyles was awarded a National Institute of Dental Research Dentist-Scientist Award, attending the University of Texas Health Science Center at San Antonio for training in Oral & Maxillofacial Surgery and a Ph.D. in Cellular and Structural Biology (2001).

Dr. Lyles is the founder (1994) and Chief Scientific Officer of Materials Evolution & Development U.S.A., Inc. He was voluntarily recalled back to active duty in August of 2003 and was assigned to the Naval Institute for Dental and Biomedical Research as Department Head, Advanced Laboratory Sciences in Great Lakes, Ill.  In 2004, CAPT Lyles deployed to Kuwait/Iraq for Operation Sandman and Operation Sandbox in support of OEF/OIF.  In January 2006, he transferred to the Bureau of Medicine & Surgery in Washington, DC.

Dr. Lyles has published over 150 scientific articles and abstracts and has over 50 issued or pending national and international patents in the fields of biomaterials, tissue engineering, drug delivery, sunscreens, diagnostics, composites, etc.  He is the 1994 winner of the Walter Lorenz Research Award from the American College of Oral and Maxillofacial Surgeons and selected the 1997 Imagineer of the Year by the Mind Science Foundation for his work in condensable dental composite materials (credited for the creation of the field of Ceromers). In 2008, CAPT Lyles was awarded the Carl A. Schlack Award by the Association of Military Surgeons of the U.S. for outstanding contributions in biomedical research and education. He was selected by the Navy Astronaut Selection Board for evaluation by NASA and also completed a M.A. in National Defense and Strategic Studies at the Naval War College in 2008. CAPT Lyles was the inaugural Sgt. Sullivan Center Awardee for his work in veteran’s health issues in 2011. In 2013, he was inducted into the College of Fellows of the American Institute of Medical and Biological Engineering (AIMBE), the first active duty military scientist to be inducted.  Dr. Lyles was recently nominated for the ADA’s Norton M. Ross Award for excellence in clinical research. He represents the Navy Reserves and the University of Rhode Island as a subject matter expert on the CDMRP, PRMRP, AFIRM, Gulf War Illness Research Panel, NASA, VHA, and other research panels.

Dr. Lyles continues to pursue his research interests and is currently involved in projects to include acoustic shielding, IR diagnostic devices, 3D additive manufacturing, and drone designs. His expertise is in biomaterials and biomedical / tissue engineering with experience in medical devices, regenerative medicine, wounds and wound healing, and cellular responses to materials.

Dr. Mark Lyles Membership on Government Panels

Congressional Directed Medical Research Programs (CDMRP)

Defense Medical Research and Development (Presently)

Gulf War Illness Research Program Panel (Presently)

Joint Warfighter Medical (Presently)

Military Burn (SME repair and treatment of severe burns; tissue engineering of full thickness grafts)

Neurotoxin Exposure TX /Parkinson’s Research (SME Neurotoxin Effects on Brain function / causes.

Orthotics and Prosthetics Outcomes (US Army SME at West Point)

Peer Reviewed Cancer (SME Cancer biology)

Peer Reviewed Medical (PRMRP panel member for last 10 years)

Peer Reviewed Orthopaedic (SME in Bone Healing and Biomaterials/ Orthopaedic Devices)

Psychological Health/Traumatic Brain Injury TBI (SME neuronal trauma and cellular responses)

Spinal Cord Injury (SME on Spinal Cord repair and Tissue Engineering of constructs)

Vision (Eye protection and drug delivery)

Joint Warfighter Medical Research Programs (Presently SME and Panel member)

JPC-1/Medical Simulation and Information Sciences Research Program

JPC-2/Military Infectious Diseases Research Program

JPC-5/Military Operational Medicine Research Program

JPC-6/Combat Casualty Care Research Program

JPC-7/Radiation Health Effects Research Program

JPC-8/Clinical and Rehabilitative Medicine Research Program

Reconstructive Transplant Research Programs

  • Presently as SME on Biomaterials and drug delivery and cellular graft rejection

Peer- Reviewed Medical Research Programs​ (PRMRP)

FY16 Topic Areas

Acute Lung Injury

Antimicrobial Resistance

Chronic Migraine and Post-Traumatic Headaches

Congenital Heart Disease

Constrictive Bronchiolitis



Emerging Infectious Diseases

Focal Segmental Glomerulosclerosis

Fragile X Syndrome

Hepatitis B

Hereditary Angioedema


Inflammatory Bowel Disease


Integrative Medicine

Interstitial Cystitis



Metals Toxicology

Mitochondrial Disease

Nanomaterials for Bone Regeneration

Non-Opioid Pain Management


Pathogen-Inactivated Dried Plasma

Polycystic Kidney Disease

Post-Traumatic Osteoarthritis

Psychotropic Medications

Pulmonary Fibrosis

Respiratory Health

Rett Syndrome

Rheumatoid Arthritis


Sleep Disorders



Vaccine Development for Infectious Disease

Vascular Malformations

Women’s Heart Disease​

 Armed Force’s Institute of Regenerative Medicine

  • Inaugural member and Panel Member (9 years)

Gulf War Illness Research Panel

  • Panel member and SME researcher in the field.

NASA Human Health and Air Quality Panel

  • Panel member (10 years) and SME / Researcher in the field.

Veteran’s Health Administration Surgery Merit Review Panel

  • Panel member (3 years) and SME / Researcher in the field.

Defense Threat Reduction Agency

  • SME on Chemical and Biological Research and researcher in the field.

Defense Advanced Research Programs Agency

  • SME on applications of molecular biology in warfare and defense, IR sensor technology, drone design, etc. and researcher in the field.

United States Air Force Medical Research Command

  • SME and VIP Medical Consultant; Finalizing 200 page Compendium of Potential Research Projects for USAF Medical Researchers; Identifying Transformational Research Technologies and Sciences.