Zheng, Guoan

Guoan Zheng, Ph.D.
United Technologies Corporation (UTC) Associate Professor
Research Interests:  Biomedical optics and instrumentation, computational imaging and sensing, microscopy and ptychography, optofluidics and chip-scale imaging solutions.
Address:   260 Glenbrook Road, Unit 3247Bronwell 217, Storrs, CT 06269-3247
Office Phone: (860) 486-6973
Office Fax: (860) 486-2500
B.S. in Electrical Engineering, Zhejiang University, 2007 
M.S. in Electrical Engineering, California Institute of Technology, 2008 
Ph.D. in Electrical Engineering, California Institute of Technology, 2013 

Research summary:

The research of the Smart Imaging Laboratory focuses on developing advanced imaging and sensing tools to address challenging measurement problems in biology, medicine, and metrology. The lab is led by Dr. Zheng, an expert in microscopy, ptychography, optical engineering, and computational imaging. The Fourier ptychography technology developed by Dr. Zheng and his colleagues is now a chapter in Goodman’s classic textbook, “Introduction to Fourier Optics (4th edition)”. The lab’s current research areas include high-throughput imaging and screening, optical physiology, super-resolution imaging, lensless ptychographic sensors, coherent diffraction imaging, and chip-scale imaging solutions. Since 2015, the lab’s research has been supported by the National Science Foundation (NSF), the National Institutes of Health (NIH), Connecticut Innovations, the UConn Research Excellence Award, and multiple industry partners.


Selected Publications (*: corresponding author):

Google Scholar Citations Link (cited over 9400 times, h-index of 49 as of Feb 2023)

  1. Chengfei Guo,Shaowei Jiang, Liming Yang, Pengming Song, Azady Pirhanov, Ruihai Wang, Tianbo Wang, Xiaopeng Shao, Qian Wu, Yong Ku Cho, Guoan Zheng*, “Depth-multiplexed ptychographic microscopy for high-throughput imaging of stacked bio-specimens on a chip,” Biosensors and Bioelectronics, 115049 (2023).
  2. (Editor’s pick) Pengming Song, Shaowei Jiang, Tianbo Wang, Chengfei Guo, Ruihai Wang, Terrance Zhang, and Guoan Zheng*, “Synthetic aperture ptychography: coded sensor translation for joint spatial-Fourier bandwidth expansion,” Photonics Research, 10(7), 1624-1632 (2022). 
  3. (Cover paper) Shaowei Jiang, Chengfei Guo, Pengming Song, Tianbo Wang, Ruihai Wang, Terrance Zhang, Qian Wu, Rishikesh Pandey, and Guoan Zheng*, “High-throughput digital pathology via a handheld, multiplexed, and AI-powered ptychographic whole slide scanner,” Lab on a Chip, 22, 2657-2670,(2022).  
  4. (Cover paper, ACS Editors’ choice) Shaowei Jiang, Chengfei Guo, Tianbo Wang, Jia Liu, Pengming Song, Terrance Zhang, Ruihai Wang, Bin Feng, and Guoan Zheng*, “Blood-coated sensor for high-throughput ptychographic cytometry on a Blu-ray disc,” ACS Sensors, 7(4), 1058-1067 (2022).  
  5. (Cover paper) Pengming Song, Chengfei Guo, Shaowei Jiang, Tianbo Wang, Patrick Hu, Derek Hu, Zibang Zhang, Bin Feng, and Guoan Zheng*, “Optofluidic ptychography on a chip,” Lab on a Chip, 21(23), 4509-4726 (2021).
  6. Shaowei Jiang, Chengfei Guo, Zichao Bian, Ruihai Wang, Jiakai Zhu, Pengming Song, Patrick Hu, Derek Hu, Zibang Zhang, Kazunori Hoshino, Bin Feng, Guoan Zheng*,  “Ptychographic sensor for large-scale lensless microbial monitoring with high spatiotemporal resolution,” Biosensors and Bioelectronics196, 113699 (2022).
  7. (Cover paper) Shaowei Jiang, Chengfei Guo*, Pengming Song, Niyun Zhou, Zichao Bian, Jiakai Zhu, Ruihai Wang, Pei Dong, Zibang Zhang, Jun Liao, Jianhua Yao, Bin Feng, Michael Murphy, and Guoan Zheng*, “Resolution-Enhanced Parallel Coded Ptychography for High-Throughput Optical Imaging,” ACS Photonics, 8(11), 3261-3271 (2021).
  8. (Cover paper) Guoan Zheng*, Cheng Shen, Shaowei Jiang, Pengming Song, and Changhuei Yang*, “Concept, implementations and applications of Fourier ptychography,” Nature Reviews Physics, 3, 207-223 (2021).
  9. Guoan Zheng*, Roarke Horstmeyer and Changhuei Yang, “Wide-field, high-resolution Fourier ptychographic microscopy,” Nature Photonics, 7, 739–745 (2013).
  10. Guoan Zheng*, Seung Ah Lee, Yaron Antebi, Micheal B. Elowitz, and Changhuei Yang, “The ePetri dish, an on-chip cellimaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proceedings of the National Academy of Sciences, 108, 16889-94 (2011).